Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 14/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5403095 | 0.99 | MC4R (0.48) | MC4RALDH1A1CNR1 | |
| SCHEMBL5411103 | 0.99 | MC4R (0.48) | MC4RALDH1A1CNR1 | |
| SCHEMBL5411304 | 0.86 | MC4R (0.50) | MC4RCNR1 | |
| SCHEMBL5414668 | 0.84 | MC4R (0.49) | MC4RALDH1A1CNR1KMT2A | |
| SCHEMBL5416495 | 0.83 | MC4R (0.51) | MC4RALDH1A1CNR1KMT2A | |
| SCHEMBL5406028 | 0.83 | MC4R (0.38) | MC4R | |
| SCHEMBL5400390 | 0.81 | MC4R (0.45) | MC4RALDH1A1 | |
| SCHEMBL5411286 | 0.80 | MC4R (0.42) | MC4RALDH1A1 | |
| SCHEMBL5413805 | 0.80 | MC4R (0.50) | MC4RCNR1 | |
| SCHEMBL5411345 | 0.79 | MC4R (0.48) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |