Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414668 | 0.99 | MC4R (0.49) | MC4RKMT2AGAAALDH1A1CNR1 | |
| SCHEMBL5414706 | 0.87 | MC4R (0.43) | MC4RKMT2AALDH1A1CNR1NPSR1 | |
| SCHEMBL5403095 | 0.84 | MC4R (0.48) | MC4RALDH1A1CNR1 | |
| SCHEMBL5411103 | 0.84 | MC4R (0.48) | MC4RALDH1A1CNR1 | |
| SCHEMBL5406153 | 0.83 | MC4R (0.47) | MC4RKMT2AALDH1A1CNR1 | |
| SCHEMBL5411342 | 0.78 | MC4R (0.49) | MC4R | |
| SCHEMBL5416498 | 0.76 | MC4R (0.70) | MC4RGAA | |
| Hydrochloric Acid SCHEMBL5411357 | 0.75 | MC4R (0.69) | MC4RGAA | |
| SCHEMBL5414672 | 0.75 | MC4R (0.69) | MC4R | |
| Hydrochloric Acid SCHEMBL7154420 | 0.74 | MC4R (0.59) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |