Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.39 |
| ▸ | PPARG | P37231 | 11/20 | 0.39 |
| ▸ | PPARA | Q07869 | 11/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PDE6A | P16499 | 1/20 | 0.33 |
| ▸ | PDE6G | P18545 | 1/20 | 0.33 |
| ▸ | PDE6B | P35913 | 1/20 | 0.33 |
| ▸ | PDE6C | P51160 | 1/20 | 0.33 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.32 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445976 | 0.89 | PPARA (0.41) | PPARDPPARGPPARAFBP1GPR119 | |
| SCHEMBL14445963 | 0.87 | PPARG (0.38) | PPARDPPARGPPARAFBP1GPR119 | |
| SCHEMBL4682098 | 0.81 | PPARG (0.43) | PPARDPPARGPPARACYP3A4 | |
| SCHEMBL14445956 | 0.81 | PPARA (0.46) | PPARDPPARGPPARAFBP1 | |
| SCHEMBL4682592 | 0.81 | PPARA (0.41) | PPARDPPARGPPARAFBP1GPR119 | |
| SCHEMBL5406496 | 0.81 | PPARA (0.41) | PPARDPPARGPPARAFBP1CYP3A4 | |
| SCHEMBL4682059 | 0.80 | PPARA (0.37) | PPARDPPARGPPARAFBP1GPR119 | |
| SCHEMBL14445987 | 0.80 | PPARA (0.51) | PPARDPPARGPPARA | |
| SCHEMBL4682146 | 0.79 | PPARA (0.45) | PPARDPPARGPPARAFBP1AGER | |
| SCHEMBL5397707 | 0.79 | PPARA (0.45) | PPARDPPARGPPARAFBP1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | claimed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |