Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5408720 | 0.92 | MAPT (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5445681 | 0.87 | MAPT (0.35) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL5410623 | 0.86 | MAPT (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| Bromide SCHEMBL5402709 | 0.85 | MAPT (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14357575 | 0.85 | MAPT (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14357594 | 0.81 | TLR7 (0.31) | MAPT | |
| SCHEMBL5447124 | 0.81 | — | — | |
| SCHEMBL5410013 | 0.81 | — | — | |
| SCHEMBL5396481 | 0.80 | LMNA (0.33) | MAPT | |
| SCHEMBL14357567 | 0.78 | SMN1; SMN2 (0.38) | MAPTSMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300469-B2 | Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres | L'OREAL, SA (FR) | 2007-11-27 | — | — | US | disclosed |