Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.39 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1346901 | 0.80 | SCN9A (0.46) | F10SCN9APRMT5PIM1PDGFRA | |
| SCHEMBL5393770 | 0.76 | SLC6A4 (0.46) | F10KDM1ASCN9APRMT5S1PR1 | |
| SCHEMBL5403306 | 0.76 | PTPN1 (0.46) | F10KDM1ASCN9APRMT5SLC6A4 | |
| SCHEMBL5955079 | 0.76 | SLC6A4 (0.45) | F10KDM1ASCN9ASLC6A4MAOB | |
| SCHEMBL27246562 | 0.74 | P2RX7 (0.44) | KDM1ASLC6A4 | |
| SCHEMBL951982 | 0.73 | SLC6A2 (0.49) | KDM1ASLC6A4 | |
| SCHEMBL951983 | 0.73 | SLC6A2 (0.49) | KDM1ASLC6A4 | |
| SCHEMBL950613 | 0.73 | BCHE (0.52) | KDM1ASLC6A4MAOBMAOA | |
| SCHEMBL950614 | 0.73 | BCHE (0.52) | KDM1ASLC6A4MAOBMAOA | |
| Hydrochloric Acid SCHEMBL950622 | 0.72 | BCHE (0.51) | KDM1ASLC6A4MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007511564-A | — | — | 2007-05-10 | — | — | JP | claimed |
| EP-1685103-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-02 | — | — | EP | claimed |
| WO-2005054190-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-16 | — | — | WO | claimed |
| EP-1685103-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005054190-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-16 | — | — | WO | disclosed |