Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 14/20 | 0.88 |
| ▸ | HTR6 | P50406 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8982893 | 0.95 | HTR7 (0.98) | HTR7HTR6POLBHTR1AADRA2A | |
| SCHEMBL5406986 | 0.95 | HTR7 (0.98) | HTR7HTR6POLBHTR1AADRA2A | |
| SCHEMBL8979740 | 0.94 | HTR7 (1.00) | HTR7HTR6POLBHTR1AADRA2A | |
| SCHEMBL10035548 | 0.91 | HTR7 (1.00) | HTR7HTR6POLBHTR1A | |
| Hydrochloric Acid SCHEMBL2140989 | 0.90 | HTR7 (0.98) | HTR7HTR6POLBHTR1A | |
| SCHEMBL8980016 | 0.84 | HTR7 (0.97) | HTR7HTR6HTR1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4228770 | 0.83 | HTR7 (0.95) | HTR7HTR6HTR1AALDH1A1 | |
| SCHEMBL8979759 | 0.83 | HTR7 (1.00) | HTR7HTR6HTR1A | |
| SCHEMBL8980718 | 0.82 | HTR7 (0.74) | HTR7HTR6POLBALDH1A1 | |
| SCHEMBL8980849 | 0.82 | HTR7 (0.74) | HTR7HTR6POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211585-B2 | 5-HT7 receptor antagonists | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-05-01 | — | — | US | disclosed |