Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5955079 | 0.84 | SLC6A4 (0.45) | FFAR1FFAR4SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL5391289 | 0.83 | FFAR4 (0.52) | FFAR4SLC6A4MAP4K3MAOBSCN9A | |
| SCHEMBL1347060 | 0.81 | FFAR1 (0.53) | FFAR1FFAR4SLC6A4CD274MEN1 | |
| SCHEMBL4488371 | 0.77 | SLC6A2 (0.60) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL4749429 | 0.77 | SLC6A2 (0.60) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL5393770 | 0.73 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3MAP4K3MAOB | |
| SCHEMBL5435829 | 0.72 | SLC6A2 (0.44) | SLC6A4MEN1KMT2ASLC6A2SLC6A3 | |
| SCHEMBL5403306 | 0.72 | PTPN1 (0.46) | SLC6A4SLC6A2SLC6A3MAP4K3MAOB | |
| SCHEMBL5668614 | 0.71 | SLC6A2 (0.51) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL16462862 | 0.71 | EPHX2 (0.40) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007511564-A | — | — | 2007-05-10 | — | — | JP | claimed |
| EP-1685103-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-02 | — | — | EP | claimed |
| WO-2005054190-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-16 | — | — | WO | claimed |
| EP-1685103-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005054190-A1 | 3-AMINOPYRROLIDONE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-16 | — | — | WO | disclosed |