Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.58 |
| ▸ | TNNC1 | P63316 | 5/20 | 0.58 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.58 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.58 |
| ▸ | GPR183 | P32249 | 1/20 | 0.58 |
| ▸ | CERS2 | Q96G23 | 1/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5407214 | 1.00 | S1PR1 (0.58) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL14593239 | 0.95 | S1PR1 (0.65) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7622550 | 0.89 | S1PR1 (0.73) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL5989142 | 0.89 | S1PR1 (0.73) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL12696488 | 0.89 | S1PR1 (0.73) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL7615757 | 0.89 | S1PR1 (0.73) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Hydrochloric Acid SCHEMBL7619659 | 0.87 | S1PR1 (0.74) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Hydrochloric Acid SCHEMBL7619592 | 0.87 | S1PR1 (0.74) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| Hydrochloric Acid SCHEMBL7615978 | 0.87 | S1PR1 (0.74) | S1PR1S1PR3S1PR4TNNC1S1PR5 | |
| SCHEMBL6272203 | 0.82 | S1PR1 (0.69) | S1PR1S1PR3S1PR4TNNC1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511473-B1 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2013-04-17 | — | — | EP | claimed |
| EP-1511473-B1 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| EP-1511473-B1 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2013-04-17 | — | — | EP | disclosed |
| US-7169817-B2 | Bis-aromatic alkanols | IRM LLC (BM) | 2007-01-30 | — | — | US | disclosed |
| US-7169817-B2 | Bis-aromatic alkanols | IRM LLC (BM) | 2007-01-30 | — | — | US | disclosed |
| US-7169817-B2 | Bis-aromatic alkanols | IRM LLC (BM) | 2007-01-30 | — | — | US | disclosed |
| EP-1511473-A2 | BIS-AROMATIC ALKANOLS | Novartis AG (CH) | 2005-03-09 | — | — | EP | disclosed |
| US-20040048857-A1 | Treatment and/or prevention of diseases or disorders mediated by lymphocyte interactions. | IRM LLC (BM) | 2004-03-11 | — | — | US | disclosed |
| WO-2003099192-A2 | BIS-AROMATIC ALKANOLS | NOVARTIS AG (CH) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048857-A1 | Treatment and/or prevention of diseases or disorders mediated by lymphocyte interactions. | CD4, HLA-DRB1, MALT1 | S1PR1 1541/4885S1PR3 1396/4885S1PR4 1604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.