Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9879787 | 0.80 | KDM4E (0.36) | KDM4EESR1 | |
| SCHEMBL1233997 | 0.80 | ADORA2A (0.37) | KDM4EADORA2AADORA2BCYP11B2AURKA | |
| SCHEMBL1232387 | 0.78 | CYP11B2 (0.33) | ADORA2AADORA2BCYP11B2 | |
| SCHEMBL20517377 | 0.78 | ADORA2A (0.36) | ADORA2AADORA2BCYP11B2 | |
| SCHEMBL31094729 | 0.77 | GRN (0.36) | KDM4EAURKARPS6KB1LMNA | |
| SCHEMBL14116468 | 0.76 | KDM4E (0.32) | KDM4EADORA2AADORA2BCYP11B2 | |
| SCHEMBL12724798 | 0.76 | CNR1 (0.32) | ADORA2AADORA2BCYP11B2 | |
| SCHEMBL1234911 | 0.75 | — | — | |
| SCHEMBL1234051 | 0.74 | CYP11B2 (0.31) | CYP11B2 | |
| SCHEMBL31094725 | 0.73 | CYP11B1 (0.41) | KDM4ECYP11B2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-7279444-B2 | Substituted benzoylpyrazoles | BAYER CROPSCIENCE GMBH (DE) | 2007-10-09 | — | — | US | disclosed |
| US-20040248740-A1 | Substituted benzoylpyrazoles | MULLER KLAUS-HELMUT (DE) | 2004-12-09 | — | — | US | disclosed |
| US-6746989-B1 | HAVE STRONG HERBICIDAL ACTIVITY AND BROAD ACTIVITY SPECTRUM WHEN APPLIED TO SOIL AND ON ABOVE-GROUND PARTS OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-06-08 | — | — | US | disclosed |
| EP-1165547-B1 | SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248740-A1 | Substituted benzoylpyrazoles | CYP1B1, CYP1A1, CYP2E1 | KDM4E 1285/4885ADORA2A 3135/4885ADORA2B 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.