Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 8/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 6/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.58 |
| ▸ | CSNK1A1 | P48729 | 6/20 | 0.58 |
| ▸ | CSNK1G2 | P78368 | 6/20 | 0.58 |
| ▸ | TAOK1 | Q7L7X3 | 6/20 | 0.58 |
| ▸ | MINK1 | Q8N4C8 | 6/20 | 0.58 |
| ▸ | PRKD2 | Q9BZL6 | 6/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.58 |
| ▸ | GSK3B | P49841 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | GSK3A | P49840 | 4/20 | 0.58 |
| ▸ | CSNK1G3 | Q9Y6M4 | 4/20 | 0.58 |
| ▸ | CSNK1G1 | Q9HCP0 | 3/20 | 0.58 |
| ▸ | CLK2 | P49760 | 1/20 | 0.58 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.58 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.58 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5410127 | 0.99 | MAPK9 (0.57) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5422780 | 0.93 | ALOX5 (0.51) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5411813 | 0.90 | ALOX5 (0.64) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5414642 | 0.90 | PRKD3 (0.56) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5413018 | 0.90 | MAPK9 (0.56) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5413029 | 0.90 | MAPK9 (0.56) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5410244 | 0.90 | MAPK9 (0.47) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5417269 | 0.90 | ADORA1 (0.48) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5426364 | 0.88 | MAPK9 (0.54) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 | |
| SCHEMBL5417185 | 0.88 | MAPK9 (0.50) | MAPK9PRKD3MAP4K4CSNK1A1CSNK1G2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186714-B2 | Imidazo[1,2-α]pyridine derivatives for the prophylaxis and treatment of herpes viral infections | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-06 | — | — | US | claimed |
| EP-1401836-B1 | IMIDAZO¬1,2-A|PYRIDINE DERIVATIVES FOR THE PROPHYLAXIS AND TREATMENT OF HERPES VIRAL INFECTIONS | SMITHKLINE BEECHAM CORP (US) | 2006-08-23 | — | — | EP | claimed |
| US-20050228004-A1 | Imidazo'1,2-a!pyridine derivatives for the prophylaxis and treatment of herpes viral infections | SMITHKLINE BEECHAM CORPORATION | 2005-10-13 | — | — | US | claimed |
| US-20070135451-A1 | Imidazo[1,2-a]Pyridine Derivatives for Treatment Of Herpes Viral Infections | GUDMUNDSSON KRISTJAN S | 2007-06-14 | — | — | US | disclosed |
| US-20070135451-A1 | Imidazo[1,2-a]Pyridine Derivatives for Treatment Of Herpes Viral Infections | GUDMUNDSSON KRISTJAN S | 2007-06-14 | — | — | US | disclosed |
| US-7186714-B2 | Imidazo[1,2-α]pyridine derivatives for the prophylaxis and treatment of herpes viral infections | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186714-B2 | Imidazo[1,2-α]pyridine derivatives for the prophylaxis and treatment of herpes viral infections | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| EP-1401836-B1 | IMIDAZO¬1,2-A|PYRIDINE DERIVATIVES FOR THE PROPHYLAXIS AND TREATMENT OF HERPES VIRAL INFECTIONS | SMITHKLINE BEECHAM CORP (US) | 2006-08-23 | — | — | EP | disclosed |
| US-20060167252-A1 | Imidazo[1,2-a]pyridine derivatives for treatment of herpes viral infections | GUDMUNDSSON KRISTJAN | 2006-07-27 | — | — | US | disclosed |
| US-20050228004-A1 | Imidazo'1,2-a!pyridine derivatives for the prophylaxis and treatment of herpes viral infections | SMITHKLINE BEECHAM CORPORATION | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135451-A1 | Imidazo[1,2-a]Pyridine Derivatives for Treatment Of Herpes Viral Infections | IRF3, IFNAR1, IL2 | MAPK9 1345/4885PRKD3 2191/4885MAP4K4 461/4885 |
| US-20050228004-A1 | Imidazo'1,2-a!pyridine derivatives for the prophylaxis and treatment of herpes viral infections | TPMT, IRF3, ZC3HAV1 | MAPK9 1412/4885PRKD3 1930/4885MAP4K4 938/4885 |
| US-20060167252-A1 | Imidazo[1,2-a]pyridine derivatives for treatment of herpes viral infections | IRF3, IFNAR1, IL2 | MAPK9 1120/4885PRKD3 2225/4885MAP4K4 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.