Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.53 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5398861 | 0.90 | F10 (0.53) | F10KLKB1NPC1POLBRAB9A | |
| SCHEMBL9940074 | 0.86 | F10 (0.51) | F10KLKB1HDAC3HDAC8NPC1 | |
| SCHEMBL5401884 | 0.86 | F10 (0.62) | F10KLKB1HDAC3HDAC8NPC1 | |
| SCHEMBL9928692 | 0.83 | F10 (0.62) | F10KLKB1 | |
| SCHEMBL9928635 | 0.83 | F10 (0.63) | F10KLKB1 | |
| SCHEMBL9979768 | 0.79 | F10 (0.76) | F10KLKB1 | |
| SCHEMBL9940059 | 0.78 | F10 (0.49) | F10KLKB1NPC1POLBRAB9A | |
| SCHEMBL5395001 | 0.77 | F10 (0.64) | F10KLKB1 | |
| SCHEMBL5407030 | 0.77 | F10 (0.63) | F10KLKB1 | |
| SCHEMBL5410337 | 0.77 | NPC1 (0.55) | F10KLKB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307074-B2 | Activated blood coagulation factor X inhibitor and also to such a pharmaceutical agent and particularly has an excellent activity by oral administration | ASTELLAS PHARMA INC. (JP) | 2007-12-11 | — | — | US | claimed |