Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940059 | 0.91 | F10 (0.49) | F10KLKB1NPC1POLBRAB9A | |
| SCHEMBL5407352 | 0.86 | F10 (0.53) | F10KLKB1HDAC3HDAC8FGFR1 | |
| SCHEMBL5398861 | 0.78 | F10 (0.53) | F10KLKB1NPC1POLBRAB9A | |
| SCHEMBL5401884 | 0.76 | F10 (0.62) | F10KLKB1HDAC3HDAC8NPC1 | |
| SCHEMBL9979768 | 0.76 | F10 (0.76) | F10KLKB1 | |
| SCHEMBL9928692 | 0.74 | F10 (0.62) | F10KLKB1 | |
| SCHEMBL9928635 | 0.72 | F10 (0.63) | F10KLKB1 | |
| SCHEMBL2321697 | 0.71 | F10 (0.61) | F10KLKB1NPC1RAB9A | |
| SCHEMBL2360325 | 0.71 | F10 (0.74) | F10KLKB1 | |
| SCHEMBL3335278 | 0.70 | F10 (0.70) | F10KLKB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43481-E1 | Diazepan derivatives or salts thereof | ASTELLAS PHARMA INC. (JP) | 2012-06-19 | — | — | US | claimed |