Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | HRH2 | P25021 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5401743 | 1.00 | HRH1 (0.46) | HRH1TDP1SLC6A2HRH2HTR2A | |
| SCHEMBL5410209 | 0.79 | CHRM3 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7531660 | 0.78 | HRH3 (0.47) | HRH1TDP1SLC6A2HRH2HTR2A | |
| SCHEMBL7535886 | 0.78 | HRH3 (0.47) | HRH1TDP1SLC6A2HRH2HTR2A | |
| SCHEMBL5407213 | 0.76 | HRH3 (0.48) | HRH1TDP1SLC6A2HRH2HTR2A | |
| SCHEMBL5414553 | 0.76 | HTT (0.47) | SMN1; SMN2CYP3A4TSHR | |
| SCHEMBL5401748 | 0.75 | SLC6A4 (0.48) | SLC6A2SLC6A4DRD3SLC6A3KCNH2 | |
| SCHEMBL5407587 | 0.75 | SLC6A4 (0.48) | SLC6A2SLC6A4DRD3SLC6A3KCNH2 | |
| SCHEMBL7332031 | 0.72 | SLC6A4 (0.57) | SLC6A2SLC6A4DRD3SLC6A3KCNH2 | |
| SCHEMBL67164 | 0.72 | SIGMAR1 (0.66) | ALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247645-B2 | Dihydropyridine derivatives | AJINOMOTO CO., INC. (JP) | 2007-07-24 | — | — | US | disclosed |