Aniline

Aniline

SCHEMBL5407834

Cc1cccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4cccc(C)c4)cc3)cc2)c1.Nc1ccccc1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
CYP3A4 P08684 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
MAPT P10636 2/20 0.55
KDM4E B2RXH2 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55
CYP2C19 P33261 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MAOA P21397 1/20 0.41
HSD17B10 Q99714 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ACHE P22303 1/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
POLB P06746 2/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL186080 0.98 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1MAPTKDM4E
Aniline SCHEMBL12274232 0.98 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL20979810 0.97 ALDH1A1 (0.60) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL6849486 0.97 ALDH1A1 (0.60) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL8364036 0.97 ALDH1A1 (0.60) ALDH1A1CYP3A4TDP1MAPTKDM4E
Benzidine SCHEMBL28942421 0.97 ALDH1A1 (0.60) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL4447994 0.94 ALDH1A1 (0.47) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL28672808 0.93 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL2701149 0.93 ALDH1A1 (0.53) ALDH1A1CYP3A4TDP1MAPTKDM4E
SCHEMBL1890559 0.91 ALDH1A1 (0.67) ALDH1A1CYP3A4TDP1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7163771-B2 Imaging members XEROX CORPORATION (US) 2007-01-16 US claimed
US-20050287453-A1 A photoconductive imaging member containing a supporting substrate, and a single layer comprised of a photogenerator component, a charge transport component, an electron transport component (alkylalcohol derivative) , and a polymer binder. XEROX CORPORATION 2005-12-29 US claimed
US-5571649-A Electrophotographic imaging member with improved underlayer XEROX CORPORATION (US) 1996-11-05 US disclosed
EP-0168224-B1 POSITIVELY CHARGED COLORED TONER COMPOSITIONS XEROX CORPORATION (US) 1992-03-11 EP disclosed
EP-0168224-A2 Positively charged colored toner compositions XEROX CORPORATION (US) 1986-01-15 EP disclosed
US-4562135-A DYE CHARGE CONTROL COMPOSITION COMPRISING A CHROIMOPHORE MOLECULE AND A TRIBOELECTRIC CHARGE ESTABLISHING GROUP XEROX CORPORATION (US) 1985-12-31 US disclosed