Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5417883 | 0.91 | SLC16A1 (0.45) | SLC16A1ALDH1A1KDM4EMAPTCYP2C9 | |
| SCHEMBL5415204 | 0.89 | SLC16A1 (0.44) | SLC16A1ALDH1A1KDM4EMAPTCYP2C9 | |
| SCHEMBL5400204 | 0.89 | SLC16A1 (0.42) | SLC16A1ALDH1A1KDM4EMAPTCYP2C9 | |
| SCHEMBL5403826 | 0.88 | SLC16A1 (0.44) | SLC16A1ALDH1A1MAPTCYP2C9MAPKAPK2 | |
| SCHEMBL5400640 | 0.88 | SLC16A1 (0.54) | SLC16A1ALDH1A1MAPTCYP2C9MAPKAPK2 | |
| SCHEMBL5411174 | 0.87 | SLC16A1 (0.49) | SLC16A1CYP2C9MAPKAPK2CAMK2BHIPK4 | |
| SCHEMBL5407668 | 0.87 | SLC16A1 (0.49) | SLC16A1ALDH1A1MAPTCYP2C9MAPKAPK2 | |
| SCHEMBL5408224 | 0.87 | SLC16A1 (0.49) | SLC16A1ALDH1A1MAPTCYP2C9MAPKAPK2 | |
| SCHEMBL5393962 | 0.86 | SLC16A1 (0.47) | SLC16A1ALDH1A1MAPTCYP2C9MAPKAPK2 | |
| SCHEMBL5400149 | 0.86 | SLC16A1 (0.49) | SLC16A1ALDH1A1MAPTCYP2C9MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |