SCHEMBL5408250

SCHEMBL5408250

C=CC(=O)OCC(C)(C)OC(C)C1CCCC(C)(C)C1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25324039 1.00 TSHR (0.33) TSHRALDH1A1TP53CYP3A4MAPK1
SCHEMBL5049182 0.84
SCHEMBL9657891 0.83
SCHEMBL16995921 0.83
SCHEMBL18316479 0.83
SCHEMBL23483313 0.83
SCHEMBL313294 0.83 ADRB2 (0.32)
SCHEMBL9656868 0.83
SCHEMBL238099 0.83
SCHEMBL5049155 0.83 MAPT (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196053-B2 Odorant compounds FIRMENICH SA (CH) 2007-03-27 US claimed
EP-1459735-B1 Odorant compounds FIRMENICH & CIE (CH) 2006-06-07 EP claimed
US-20040186043-A1 Perfuming ingredient is (1S,1'R)-2-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxy]-2-methylpropyl 2-propenoate FIRMENICH SA (CH) 2004-09-23 US claimed
EP-1459735-A1 Odorant compounds FIRMENICH SA (CH) 2004-09-22 EP claimed
US-10576179-B2 Relating to organic compounds Givaudan, S.A. (CH) 2020-03-03 US disclosed
US-20180078666-A1 RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2018-03-22 US disclosed
EP-3294347-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2018-03-21 EP disclosed
WO-2016180893-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2016-11-17 WO disclosed
US-7196053-B2 Odorant compounds FIRMENICH SA (CH) 2007-03-27 US disclosed
EP-1459735-B1 Odorant compounds FIRMENICH & CIE (CH) 2006-06-07 EP disclosed
US-20040186043-A1 Perfuming ingredient is (1S,1'R)-2-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxy]-2-methylpropyl 2-propenoate FIRMENICH SA (CH) 2004-09-23 US disclosed
EP-1459735-A1 Odorant compounds FIRMENICH SA (CH) 2004-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040186043-A1 Perfuming ingredient is (1S,1'R)-2-[1-(3',3'-dimethyl-1'-cyclohexyl)ethoxy]-2-methylpropyl 2-propenoate CYP1A1, CBR1, CYP1B1 TSHR 4468/4885ALDH1A1 359/4885TP53 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.