Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593473 | 0.86 | MC4R (0.77) | MC4RALDH1A1LMNATP53SLC6A2 | |
| SCHEMBL5421309 | 0.81 | MC4R (0.54) | MC4RALDH1A1LMNATP53TSHR | |
| SCHEMBL14593479 | 0.77 | MC4R (0.64) | MC4RALDH1A1LMNASLC6A2SLC6A4 | |
| SCHEMBL14593459 | 0.76 | MC4R (0.62) | MC4RSLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL5400732 | 0.74 | MC4R (0.76) | MC4RSLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL14593469 | 0.72 | MC4R (0.75) | MC4RSLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL5411624 | 0.72 | MC4R (0.59) | MC4RLMNATP53SLC6A2SLC6A4 | |
| SCHEMBL5413699 | 0.72 | MC4R (0.59) | MC4RSLC6A2SLC6A4KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2848822 | 0.72 | NPY2R (0.40) | MC4RSLC6A2SLC6A4KCNH2CYP2D6 | |
| SCHEMBL31647364 | 0.70 | MC4R (0.41) | MC4RSLC6A2SLC6A4KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |