Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | GLA | P06280 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 3/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 3/20 | 0.47 |
| ▸ | SQOR | Q9Y6N5 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414611 | 0.93 | HPGD (0.54) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL5390378 | 0.92 | ADORA2A (0.57) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL29442321 | 0.86 | KDM4E (0.52) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL14385653 | 0.86 | ALDH1A1 (0.53) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL29442296 | 0.86 | KMT2A (0.48) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL22215932 | 0.86 | KMT2A (0.48) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL14385234 | 0.86 | ADORA2A (0.49) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL14385254 | 0.85 | KMT2A (0.58) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL14385649 | 0.85 | ADORA2A (0.46) | ADORA2AADORA1ALDH1A1HPGDKDM4E | |
| SCHEMBL14385269 | 0.84 | KMT2A (0.49) | ADORA2AADORA1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007124545-A1 | INTEGRASE INHIBITORS - 2 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007124545-A1 | INTEGRASE INHIBITORS - 2 | AVEXA LIMITED (AU) | 2007-11-08 | — | — | WO | disclosed |