Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | PLA2G6 | O60733 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398286 | 1.00 | KDM1A (0.46) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL5404231 | 0.89 | KDM1A (0.43) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL16398217 | 0.88 | KDM1A (0.42) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL16398218 | 0.88 | KDM1A (0.42) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL17747357 | 0.86 | KDM1A (0.41) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL17747353 | 0.86 | KDM1A (0.41) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL17747355 | 0.86 | KDM1A (0.41) | KDM1ASLC6A4SLC6A2SLC6A3DRD2 | |
| SCHEMBL6758128 | 0.83 | PTPN22 (0.43) | ALDH1A1MAPTHPGDNPSR1PKM | |
| SCHEMBL6755917 | 0.79 | IDO1 (0.45) | IDO1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL1630256 | 0.77 | CYP1A2 (0.41) | MTNR1AMTNR1BCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004120-B1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | UNIV NANYANG TECH (SG) | 2018-08-29 | — | — | EP | disclosed |
| CN-105658656-A | 1, 1' -spiroindane-7, 7-bisphosphine oxides as highly active supporting ligands in palladium-catalyzed asymmetric Heck reactions | 南洋理工大学 | 2016-06-08 | — | — | CN | disclosed |
| US-20160136629-A1 | SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-05-19 | — | — | US | disclosed |
| EP-3004120-A1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | Nanyang Technological University (SG) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014196930-A1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-12-11 | — | — | WO | disclosed |
| US-7192684-B2 | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2007-03-20 | — | — | US | disclosed |
| US-20040067436-A1 | Polymerizable silicon-containing compound, manufacturing method, polymer, resist composition and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| US-4994539-A | Ethylene-unsaturated aromatic copolymer | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0180771-B1 | METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS | Nippon Petrochemicals Co., Ltd. (JP) | 1989-08-02 | — | — | EP | disclosed |
| EP-0174378-B1 | ELECTRICAL-INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1989-07-12 | — | — | EP | disclosed |
| EP-0114385-B1 | ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-08-05 | — | — | EP | disclosed |
| EP-0103868-B1 | IMPROVED ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |
| EP-0180771-A1 | Method for improving impulse breakdown strength of electrically insulating materials | Nippon Petrochemicals Co., Ltd. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0174378-A1 | Electrical-insulating oil and oil-filled electrical appliances | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1986-03-19 | — | — | EP | disclosed |
| US-4543207-A | ORGANIC ACID ESTERS, AROMATIC ETHERS, ANIMAL OILS, VEGETABLE OILS,AND AROMATIC OLEFINS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1985-09-24 | — | — | US | disclosed |
| US-4506107-A | CAPACITORS, CABLES, TRANSFORMERS, PLASTICS | NIPPON PETROCHEMICAL COMPANY, LIMITED (JP) | 1985-03-19 | — | — | US | disclosed |
| US-4493943-A | MIXTURES OF DIARYLALKANES AND AROMATIC MONO-OR DI-OLEFINS | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0114385-A2 | Electrical insulating oil and oil-filled electrical appliances | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1984-08-01 | — | — | EP | disclosed |
| EP-0103868-A2 | Improved electrical insulating oil and oil-filled electrical appliances | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1984-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160136629-A1 | SPIRO-1,1'-BINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALADIUM-CATALYZED ASYMMETRIC HECK REACTION | SBK1, SIK1, PDPK1 | KDM1A 2668/4885SLC6A4 3073/4885SLC6A2 4126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.