Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 8/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.65 |
| ▸ | PLG | P00747 | 7/20 | 0.60 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 4/20 | 0.57 |
| ▸ | F10 | P00742 | 4/20 | 0.57 |
| ▸ | PLAT | P00750 | 3/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5408990 | 0.91 | PLAU (0.52) | PLAUPRSS1PLGCHEK2F2 | |
| SCHEMBL14355116 | 0.87 | PLAU (0.83) | PLAUPRSS1PLGCHEK2F2 | |
| SCHEMBL24312880 | 0.86 | PLAU (0.81) | PLAUPRSS1PLGCHEK2F2 | |
| SCHEMBL14519390 | 0.86 | PLAU (0.86) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL13167166 | 0.85 | PLAU (0.53) | PLAUPRSS1PLGF2F10 | |
| Acetic Acid SCHEMBL6510589 | 0.85 | PLAU (0.49) | PLAUPRSS1PLGCHEK2F2 | |
| SCHEMBL5517426 | 0.85 | PLAU (0.83) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL12348362 | 0.82 | PLAU (0.79) | PLAUPRSS1PLGF2F10 | |
| SCHEMBL14519365 | 0.81 | PLAU (0.73) | PLAUPRSS1PLGCHEK2F2 | |
| SCHEMBL14599555 | 0.81 | PLAU (0.77) | PLAUPRSS1PLGCHEK2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509176-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1682518-A1 | DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-07-26 | — | — | EP | claimed |
| WO-2005040132-A1 | DICATIONIC TRIARYL ANALOGS AS ANTI-PROTOZOAN AGENTS | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-05-06 | — | — | WO | claimed |