Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409642 | 1.00 | TSHR (0.53) | TSHRTP53ESR1ESR2CYP1A1 | |
| SCHEMBL5422299 | 1.00 | TSHR (0.53) | TSHRTP53ESR1ESR2CYP1A1 | |
| SCHEMBL5422294 | 1.00 | TSHR (0.53) | TSHRTP53ESR1ESR2CYP1A1 | |
| SCHEMBL5409637 | 1.00 | TSHR (0.53) | TSHRTP53ESR1ESR2CYP1A1 | |
| SCHEMBL28702128 | 0.86 | TSHR (0.47) | TSHRTP53ESR1ESR2CYP1A1 | |
| SCHEMBL11687891 | 0.86 | ESR1 (0.51) | TSHRTP53ESR1ESR2CYP1A1 | |
| SCHEMBL12575893 | 0.83 | ELANE (0.54) | TSHRESR1ESR2SLC6A3LMNA | |
| SCHEMBL13706402 | 0.83 | ELANE (0.54) | TSHRESR1ESR2SLC6A3LMNA | |
| SCHEMBL8078600 | 0.81 | NPC1 (0.55) | TSHRTP53ESR1ESR2CYP1A1 | |
| SCHEMBL1082231 | 0.81 | TSHR (0.53) | TSHRTP53ESR1ESR2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173141-B2 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2007-02-06 | — | — | US | disclosed |
| US-20060205816-A1 | Chiral lactones | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205816-A1 | Chiral lactones | HSD11B2, HSD11B1, HSD17B2 | TSHR 3698/4885TP53 1819/4885ESR1 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.