⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419423 | 0.97 | — | — | |
| SCHEMBL18660488 | 0.97 | — | — | |
| SCHEMBL8978433 | 0.97 | KDM4E (0.50) | — | |
| SCHEMBL2355 | 0.97 | — | — | |
| Benzene SCHEMBL28342353 | 0.94 | LMNA (0.48) | — | |
| Hydrochloric Acid SCHEMBL1868855 | 0.94 | — | — | |
| SCHEMBL1146004 | 0.94 | — | — | |
| SCHEMBL8504418 | 0.94 | — | — | |
| SCHEMBL7209441 | 0.94 | — | — | |
| Water SCHEMBL7171316 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8898047-B2 | Methods for identifying inhibitors against viruses that use a class I fusion protein | JANSSEN PHARMACEUTICALS NV (BE) | 2014-11-25 | — | — | US | claimed |
| EP-2257809-B1 | METHOD FOR IDENTIFYING INHIBITORS AGAINST VIRUSES THAT USE A CLASS I FUSION PROTEIN | TIBOTEC PHARM LTD (IE) | 2012-02-08 | — | — | EP | claimed |
| US-20110009408-A1 | METHODS FOR IDENTIFIYING INHIBITORS AGAINST VIRUSES THAT USE A CLASS I FUSION PROTEIN | JANSSEN SCIENCES IRELAND UC (IE) | 2011-01-13 | — | — | US | claimed |
| CN-114478372-A | Asymmetric preparation method of pyridinol nitrogen oxide | 凯特立斯（深圳）科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478372-A | Asymmetric preparation method of pyridinol nitrogen oxide | 凯特立斯（深圳）科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-114478372-A | Asymmetric preparation method of pyridinol nitrogen oxide | 凯特立斯（深圳）科技有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-8898047-B2 | Methods for identifying inhibitors against viruses that use a class I fusion protein | JANSSEN PHARMACEUTICALS NV (BE) | 2014-11-25 | — | — | US | disclosed |
| EP-2257809-B1 | METHOD FOR IDENTIFYING INHIBITORS AGAINST VIRUSES THAT USE A CLASS I FUSION PROTEIN | TIBOTEC PHARM LTD (IE) | 2012-02-08 | — | — | EP | disclosed |
| US-20110009408-A1 | METHODS FOR IDENTIFIYING INHIBITORS AGAINST VIRUSES THAT USE A CLASS I FUSION PROTEIN | JANSSEN SCIENCES IRELAND UC (IE) | 2011-01-13 | — | — | US | disclosed |