SCHEMBL5409883

SCHEMBL5409883

CCCn1ncc(N)c1NCC(O)CC

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
TLR7 Q9NYK1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5399058 0.90 POLB (0.32) POLB
SCHEMBL14357584 0.89 TLR7 (0.30) TLR7
SCHEMBL5406437 0.88 TLR7 (0.32) TLR7
SCHEMBL5443080 0.87 TLR7 (0.32) TLR7
SCHEMBL5442966 0.87
SCHEMBL14357594 0.84 TLR7 (0.31) TLR7
SCHEMBL5403260 0.84 POLB (0.32) POLB
SCHEMBL5407351 0.84 POLB (0.33) POLB
SCHEMBL5401359 0.81 KDM4E (0.32) POLB
SCHEMBL5403246 0.80 POLB (0.35) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed