SCHEMBL5406437

SCHEMBL5406437

CCC(O)CNc1c(N)cnn1CC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 1/20 0.32
XDH P47989 1/20 0.31
PDE4B Q07343 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5443080 0.90 TLR7 (0.32) TLR7
SCHEMBL5409883 0.88 POLB (0.33) TLR7
SCHEMBL14357594 0.87 TLR7 (0.31) TLR7
SCHEMBL5410623 0.86 MAPT (0.38) XDHPDE4B
SCHEMBL14357584 0.86 TLR7 (0.30) TLR7
Bromide SCHEMBL5402709 0.85 MAPT (0.38) XDHPDE4B
SCHEMBL5442966 0.84
SCHEMBL5405055 0.84 PDE4B (0.32) XDHPDE4B
SCHEMBL5405419 0.84 PDE4B (0.32) XDHPDE4B
SCHEMBL5409807 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed
US-7300469-B2 Diaminopyrazole compounds and the use thereof in the oxidation dyeing of keratinous fibres L'OREAL, SA (FR) 2007-11-27 US disclosed