Urethane

Urethane

SCHEMBL541145

C1COC1.CCOC(N)=O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.71
TSHR P16473 3/20 0.45
ALDH1A1 P00352 5/20 0.42
RECQL P46063 1/20 0.41
LMNA P02545 5/20 0.40
HSD17B10 Q99714 2/20 0.40
RAB9A P51151 2/20 0.39
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GAA P10253 2/20 0.39
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
CYP2C19 P33261 2/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL41478 0.93
Urethane SCHEMBL17164841 0.93 ALOX15 (0.75) ALOX15TSHRALDH1A1RECQLLMNA
Urethane SCHEMBL7059731 0.91 ALOX15 (0.65) ALOX15TSHRALDH1A1RECQLLMNA
Urethane SCHEMBL10414976 0.91 ALOX15 (0.71) ALOX15TSHRALDH1A1RECQLLMNA
Dioxane SCHEMBL28816032 0.91 ALOX15 (0.71) ALOX15TSHRALDH1A1RECQLLMNA
Dioxane SCHEMBL29117360 0.88 ALOX15 (0.68) ALOX15TSHRALDH1A1RECQLLMNA
Urethane SCHEMBL7866246 0.87
Cyclohexane SCHEMBL16242963 0.87 ALOX15 (0.83) ALOX15TSHRALDH1A1LMNAHSD17B10
Urethane SCHEMBL5597551 0.87 ALOX15 (0.83) ALOX15TSHRALDH1A1LMNAHSD17B10
Urethane SCHEMBL250833 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1546229-B1 POLYURETHANE AND POLYURETHANE-UREA ELASTOMERS FROM POLYTRIMETHYLENE ETHER GLYCOL DU PONT (US) 2012-02-08 EP claimed
EP-1546229-A4 POLYURETHANE AND POLYURETHANE-UREA ELASTOMERS FROM POLYTRIMETHYLENE ETHER GLYCOL DU PONT (US) 2007-09-19 EP claimed
EP-1546229-A1 POLYURETHANE AND POLYURETHANE-UREA ELASTOMERS FROM POLYTRIMETHYLENE ETHER GLYCOL E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-06-29 EP claimed
WO-2004014979-A1 POLYURETHANE AND POLYURETHANE-UREA ELASTOMERS FROM POLYTRIMETHYLENE ETHER GLYCOL E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-19 WO claimed
EP-1546229-A4 POLYURETHANE AND POLYURETHANE-UREA ELASTOMERS FROM POLYTRIMETHYLENE ETHER GLYCOL DU PONT (US) 2007-09-19 EP disclosed
EP-1546229-A1 POLYURETHANE AND POLYURETHANE-UREA ELASTOMERS FROM POLYTRIMETHYLENE ETHER GLYCOL E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-06-29 EP disclosed
WO-2004014979-A1 POLYURETHANE AND POLYURETHANE-UREA ELASTOMERS FROM POLYTRIMETHYLENE ETHER GLYCOL E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-02-19 WO disclosed