Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14530098 | 0.86 | MAPK14 (0.49) | MEN1KMT2ACNR1CNR2MAPK14 | |
| SCHEMBL5170995 | 0.84 | CNR1 (0.50) | MEN1KMT2ACNR1CNR2MAPK14 | |
| Hydrochloric Acid SCHEMBL5332847 | 0.83 | CNR1 (0.49) | MEN1KMT2ACNR1CNR2MAPK14 | |
| SCHEMBL1856087 | 0.79 | POLB (0.64) | MEN1KMT2APOLBKDM4E | |
| SCHEMBL5171331 | 0.77 | CNR1 (0.51) | MEN1KMT2ACNR1CNR2MAPK14 | |
| SCHEMBL5172571 | 0.75 | CYP1A2 (0.59) | MEN1KMT2ACNR1CNR2KDM4E | |
| SCHEMBL11171967 | 0.75 | NPC1 (0.59) | MEN1KMT2APOLBTSHR | |
| SCHEMBL10130103 | 0.74 | CNR1 (0.73) | CNR1CNR2MAPK14MAPK13MAPK12 | |
| SCHEMBL5313808 | 0.73 | KDM4E (0.51) | MEN1KMT2APOLBKDM4ETSHR | |
| SCHEMBL10130090 | 0.73 | MAPK14 (0.70) | KMT2ACNR1CNR2MAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007054836-A2 | 1, 2-SUBSTITUTED NAPHTHALENE DERIVATIVES WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-05-18 | — | — | WO | disclosed |