Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5332847 | 0.99 | CNR1 (0.49) | CNR1CNR2KMT2AMEN1MAPK14 | |
| SCHEMBL5412929 | 0.84 | MEN1 (0.55) | CNR1CNR2KMT2AMEN1MAPK14 | |
| SCHEMBL14539908 | 0.80 | CNR2 (0.46) | CNR1CNR2KMT2AMAPK14HPGDS | |
| SCHEMBL14530098 | 0.79 | MAPK14 (0.49) | CNR1CNR2KMT2AMEN1MAPK14 | |
| SCHEMBL5171331 | 0.77 | CNR1 (0.51) | CNR1CNR2KMT2AMEN1MAPK14 | |
| SCHEMBL5172351 | 0.77 | PIK3CA (0.45) | KMT2AMEN1KDM4ETSHRLMNA | |
| SCHEMBL4566793 | 0.73 | MAPK14 (0.66) | CNR1CNR2MAPK14MAPK13MAPK12 | |
| SCHEMBL30009966 | 0.73 | MAPK14 (0.66) | CNR1CNR2MAPK14MAPK13MAPK12 | |
| SCHEMBL5172571 | 0.73 | CYP1A2 (0.59) | CNR1CNR2KMT2AMEN1KDM4E | |
| SCHEMBL11171967 | 0.72 | NPC1 (0.59) | KMT2AMEN1POLBTSHRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1777219-A1 | 1,2-Substituted naphthalene derivatives with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2007-04-25 | — | — | EP | claimed |
| WO-2007054836-A2 | 1, 2-SUBSTITUTED NAPHTHALENE DERIVATIVES WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-05-18 | — | — | WO | disclosed |
| WO-2007054836-A2 | 1, 2-SUBSTITUTED NAPHTHALENE DERIVATIVES WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2007-05-18 | — | — | WO | disclosed |
| EP-1777219-A1 | 1,2-Substituted naphthalene derivatives with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2007-04-25 | — | — | EP | disclosed |