Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1298904 | 0.85 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| Fumaric Acid SCHEMBL1300041 | 0.78 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| Fumaric Acid SCHEMBL1300044 | 0.78 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL1298937 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL15800618 | 0.76 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL4115335 | 0.74 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL12107936 | 0.74 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL6972956 | 0.73 | CNR2 (0.40) | ALDH1A1L3MBTL1MAPTKDM4EKMT2A | |
| SCHEMBL29360890 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4EGAACA12CA2 | |
| SCHEMBL12782495 | 0.70 | CNR2 (0.42) | ALDH1A1KDM4EHPGDLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044015-A9 | TREATING OR PREVENTING RENAL CANCER USING A DIMETHANE SULFONATE | US GOV HEALTH & HUMAN SERV (US) | 2007-05-31 | — | — | WO | claimed |