Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 12/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541388 | 1.00 | CASR (0.43) | CASRBRD4MCL1BADPPARG | |
| SCHEMBL541647 | 0.91 | CASR (0.42) | CASRPPARG | |
| SCHEMBL541857 | 0.91 | CASR (0.42) | CASRPPARG | |
| SCHEMBL541525 | 0.90 | CASR (0.43) | CASRPPARGCNR2 | |
| SCHEMBL541526 | 0.90 | CASR (0.43) | CASRPPARGCNR2 | |
| SCHEMBL541460 | 0.87 | CASR (0.40) | CASRMCL1BADPPARGCNR2 | |
| SCHEMBL541004 | 0.87 | CASR (0.40) | CASRMCL1BADPPARGCNR2 | |
| SCHEMBL541702 | 0.87 | CASR (0.40) | CASRPPARG | |
| SCHEMBL541302 | 0.87 | CASR (0.40) | CASRPPARG | |
| SCHEMBL541318 | 0.87 | CASR (0.53) | CASRBRD4PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509518-B1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC (US) | 2012-02-08 | — | — | EP | claimed |