Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14504043 | 1.00 | AR (0.55) | ARKCNH2 | |
| SCHEMBL5414088 | 1.00 | AR (0.55) | ARKCNH2 | |
| SCHEMBL5405626 | 0.90 | AR (0.54) | ARKCNH2 | |
| SCHEMBL5405620 | 0.90 | AR (0.54) | ARKCNH2 | |
| SCHEMBL5346337 | 0.84 | AR (0.53) | ARKCNH2 | |
| SCHEMBL14336560 | 0.84 | AR (0.53) | ARKCNH2 | |
| SCHEMBL5346343 | 0.84 | AR (0.53) | ARKCNH2 | |
| SCHEMBL5344016 | 0.82 | AR (0.55) | ARKCNH2 | |
| SCHEMBL5344028 | 0.82 | AR (0.55) | ARKCNH2 | |
| SCHEMBL14504025 | 0.82 | AR (0.55) | ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217720-B2 | 17-heterocyclic-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2007-05-15 | — | — | US | claimed |
| US-20060287349-A1 | 17-HETEROCYCLIC-4-AZASTEROID DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2006-12-21 | — | — | US | claimed |
| US-7217720-B2 | 17-heterocyclic-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20060287349-A1 | 17-HETEROCYCLIC-4-AZASTEROID DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | MERCK SHARP & DOHME CORP. | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287349-A1 | 17-HETEROCYCLIC-4-AZASTEROID DERIVATIVES AS ANDROGEN RECEPTOR MODULATORS | AR, SHBG, NR5A1 | AR 1/4885KCNH2 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.