Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.39 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SDHA | P31040 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541492 | 1.00 | CALML3 (0.39) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL542065 | 0.92 | CALML3 (0.38) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL541495 | 0.86 | CALML3 (0.39) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL541496 | 0.86 | CALML3 (0.39) | CALML3MAOBMAOALMNAPTGS1 | |
| Cadazolid SCHEMBL541618 | 0.85 | KDM4E (0.52) | LMNATOP2BKDM4EMAPTHPGD | |
| Cadazolid SCHEMBL541681 | 0.85 | KDM4E (0.52) | LMNATOP2BKDM4EMAPTHPGD | |
| Cadazolid SCHEMBL29379581 | 0.85 | KDM4E (0.52) | LMNATOP2BKDM4EMAPTHPGD | |
| SCHEMBL541524 | 0.81 | KDM4E (0.49) | LMNATOP2BKDM4EMAPTHPGD | |
| SCHEMBL541556 | 0.81 | KDM4E (0.49) | LMNATOP2BKDM4EMAPTHPGD | |
| SCHEMBL541557 | 0.81 | KDM4E (0.49) | LMNATOP2BKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247578-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE-DERIVATIVES AND THEIR USES AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD. (CH) | 2009-10-01 | — | — | US | claimed |
| CN-101535305-A | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-16 | — | — | CN | claimed |
| CN-101535305-B | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD | 2013-09-18 | — | — | CN | disclosed |
| US-8124623-B2 | 5-hydroxymethyl-oxazolidin-2-one-derivatives and their uses as antibacterials | ACTELION PHARMACEUTICALS LTD. (CH) | 2012-02-28 | — | — | US | disclosed |
| EP-2086968-B1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2012-02-08 | — | — | EP | disclosed |
| US-20090247578-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE-DERIVATIVES AND THEIR USES AS ANTIBACTERIALS | ACTELION PHARMACEUTICALS LTD. (CH) | 2009-10-01 | — | — | US | disclosed |
| CN-101535305-A | 5-hydroxymethyl-oxazolidin-2-one derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2009-09-16 | — | — | CN | disclosed |
| EP-2086968-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008056335-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247578-A1 | 5-HYDROXYMETHYL-OXAZOLIDIN-2-ONE-DERIVATIVES AND THEIR USES AS ANTIBACTERIALS | OGFOD1, OXGR1, ODC1 | CALML3 3066/4885MAOB 846/4885MAOA 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.