Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 10/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.41 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.41 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.41 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.41 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.41 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.41 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.41 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | KRAS | P01116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541602 | 1.00 | CASR (0.55) | CASRPPARGATP1A1ATP1B1ATP1A3 | |
| SCHEMBL541458 | 0.91 | CASR (0.48) | CASRPPARGSERPINE1 | |
| SCHEMBL541459 | 0.91 | CASR (0.48) | CASRPPARGSERPINE1 | |
| SCHEMBL541461 | 0.88 | CASR (0.47) | CASRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL541235 | 0.88 | CASR (0.47) | CASRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL541645 | 0.87 | CASR (0.61) | CASRPPARGSMN1; SMN2MEN1KMT2A | |
| SCHEMBL541938 | 0.87 | CASR (0.61) | CASRPPARGSMN1; SMN2MEN1KMT2A | |
| SCHEMBL541305 | 0.87 | CASR (0.42) | CASRPPARG | |
| SCHEMBL541306 | 0.87 | CASR (0.42) | CASRPPARG | |
| SCHEMBL3946612 | 0.82 | CASR (0.49) | CASRPPARGSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509518-B1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC (US) | 2012-02-08 | — | — | EP | claimed |