Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.50 |
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4028983 | 0.78 | ESR1 (0.70) | ESR1RORCESR2MEN1MAPT | |
| SCHEMBL13106166 | 0.74 | ALDH1A1 (0.44) | KDM4EALDH1A1MAPK13EIF2AK2MAPK12 | |
| SCHEMBL4025528 | 0.71 | NAMPT (0.50) | ESR1RORCALDH1A1NAMPTKMT2A | |
| SCHEMBL4027782 | 0.69 | SCN9A (0.57) | ESR1KDM4EALDH1A1USP7MEN1 | |
| SCHEMBL4030717 | 0.69 | MAPK1 (0.53) | ESR1KDM4EALDH1A1NAMPTMEN1 | |
| SCHEMBL15064423 | 0.68 | NAMPT (0.53) | ESR1KDM4EALDH1A1NAMPTMEN1 | |
| SCHEMBL4035239 | 0.68 | ESR1 (0.80) | ESR1RORCESR2MEN1MAPT | |
| SCHEMBL4025667 | 0.67 | ESR1 (1.00) | ESR1RORCESR2MEN1MAPT | |
| SCHEMBL6195448 | 0.66 | TRPV1 (0.56) | ESR1 | |
| SCHEMBL4030678 | 0.66 | ESR1 (0.77) | ESR1RORCESR2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241791-B2 | Substituted 4-(indazol-3-yl)phenols | WYETH (US) | 2007-07-10 | — | — | US | claimed |