Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046598 | 0.91 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL19248179 | 0.91 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL1044990 | 0.90 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL1042152 | 0.85 | HSD11B1 (0.76) | HSD11B1HSD11B2 | |
| SCHEMBL1046268 | 0.83 | HSD11B1 (0.70) | HSD11B1HSD11B2 | |
| SCHEMBL1045626 | 0.83 | HSD11B1 (0.73) | HSD11B1HSD11B2 | |
| SCHEMBL1044672 | 0.83 | HSD11B1 (0.74) | HSD11B1HSD11B2 | |
| SCHEMBL1044753 | 0.82 | HSD11B1 (0.71) | HSD11B1HSD11B2 | |
| SCHEMBL2830494 | 0.81 | HSD11B1 (0.86) | HSD11B1HSD11B2 | |
| SCHEMBL1077064 | 0.81 | HSD11B1 (1.00) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1846363-A2 | ADAMANTYL DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | ABBOTT LABORATORIES (US) | 2007-10-24 | — | — | EP | disclosed |
| WO-2006074244-A2 | ADAMANTYL DERIVATIVES AS INHIBITORS OF THE 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 ENZYME | ABBOTT LABORATORIES (US) | 2006-07-13 | — | — | WO | disclosed |