Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445306 | 0.92 | KDM4E (0.37) | ALDH1A1KDM4EHPGDHSD17B10ALOX15 | |
| SCHEMBL14445305 | 0.87 | CYP2C9 (0.33) | BPTFCNR1CNR2HRH3 | |
| SCHEMBL5707080 | 0.85 | CYP1A2 (0.35) | KDM4ECDK1HRH4 | |
| SCHEMBL14445295 | 0.84 | CNR1 (0.33) | BPTFCNR1CNR2 | |
| SCHEMBL14445304 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10BPTF | |
| SCHEMBL14445298 | 0.81 | CNR1 (0.33) | ALDH1A1BPTFCNR1CNR2 | |
| SCHEMBL5405380 | 0.80 | HRH4 (0.34) | ALDH1A1CDK1HRH4 | |
| SCHEMBL5427359 | 0.80 | CNR1 (0.34) | BPTFCNR1CNR2 | |
| SCHEMBL14445360 | 0.80 | CNR1 (0.34) | ALDH1A1KDM4EHPGDALOX15CDK1 | |
| SCHEMBL5418831 | 0.79 | CYP2C9 (0.35) | BPTF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |
| US-7250063-B2 | Diaminopyrazole derivatives and their use for oxidation dyeing of keratinous fibres | L'OREAL (FR) | 2007-07-31 | — | — | US | disclosed |