SCHEMBL542009

SCHEMBL542009

CC(C)c1nc(N)c2[nH]cnc2n1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.59
GDA Q9Y2T3 1/20 0.59
CDK2 P24941 7/20 0.47
CDK1 P06493 6/20 0.47
CCNB1 P14635 6/20 0.47
CCNA2 P20248 6/20 0.47
CCNA1 P78396 6/20 0.47
PI4KA P42356 2/20 0.47
PI4K2B Q8TCG2 2/20 0.47
PI4K2A Q9BTU6 2/20 0.47
PI4KB Q9UBF8 2/20 0.47
LMNA P02545 1/20 0.47
DRD3 P35462 1/20 0.47
XDH P47989 1/20 0.47
LRRK2 Q5S007 1/20 0.47
MAP3K5 Q99683 1/20 0.44
DPP4 P27487 1/20 0.43
PNP P00491 1/20 0.42
POLA1 P09884 2/20 0.40
CYP1A2 P05177 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29721618 0.86 PDPK1 (0.56) PDPK1GDACDK2CDK1CCNB1
SCHEMBL5509118 0.86 PDPK1 (0.56) PDPK1GDACDK2CDK1CCNB1
SCHEMBL28004538 0.85 PDPK1 (0.54) PDPK1GDACDK2CDK1CCNB1
SCHEMBL7165321 0.83 PDPK1 (0.53) PDPK1GDACDK2CDK1CCNB1
SCHEMBL28731074 0.82 PDPK1 (0.59) PDPK1GDACDK2CDK1CCNB1
SCHEMBL48131 0.81 PDPK1 (0.50) PDPK1GDACDK2CDK1CCNB1
SCHEMBL24995361 0.80 CDK2 (0.41) PDPK1GDACDK2CDK1CCNB1
SCHEMBL4364347 0.80 CDK1 (0.49) PDPK1GDACDK2CDK1CCNB1
SCHEMBL13269009 0.80 PDPK1 (0.49) PDPK1GDACDK2CDK1CCNB1
SCHEMBL13268765 0.80 PDPK1 (0.49) PDPK1GDACDK2CDK1CCNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 739 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4041249-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES The Scripps Research Institute (US) 2022-08-17 EP claimed
US-20220243244-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES NATIONAL INSTITUTES OF HEALTH 2022-08-04 US claimed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN claimed
WO-2021072167-A1 COMPOSITIONS AND METHODS FOR IN VIVO SYNTHESIS OF UNNATURAL POLYPEPTIDES THE SCRIPPS RESEARCH INSTITUTE (US) 2021-04-15 WO claimed
WO-2012099630-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING A RETROVIRUS INFECTION UNIVERSITY OF ROCHESTER (US) 2012-07-26 WO claimed
US-7223849-B1 Oligonucleotides from the untranslated regions of housekeeping genes and methods of using same to modulate cell growth GENESENSE TECHNOLOGIES INC. (CA) 2007-05-29 US claimed
US-7067497-B2 Modulation of telomere length by oligonucleotides having a G-core sequence ISIS PHARMACEUTICALS, INC. (US) 2006-06-27 US claimed
US-20040049022-A1 Composition & methods for treatment and screening NYCE JONATHAN W (US) 2004-03-11 US claimed
WO-2004011613-A2 COMPOSITION & METHODS FOR TREATMENT AND SCREENING EPIGENESIS PHARMACEUTICALS, INC. (US) 2004-02-05 WO claimed
US-6566514-B1 Antisense oligonucleotides for use in the treatment of tumors GENESENSE TECHNOLOGIES INC. (CA) 2003-05-20 US claimed
WO-2026101887-A1 NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME ILLUMINA, INC. (US) 2026-05-15 WO disclosed
US-20260132223-A1 CLEAVABLE LINKERS FOR THE TETHERING OF POLYMERASES TO NUCLEOTIDES ANSA BIOTECHNOLOGIES INC (US) 2026-05-14 US disclosed
US-20260125412-A1 NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME ILLUMINA, INC. (US) 2026-05-07 US disclosed
EP-4735626-A1 USING APERTURES TO CAPTURE POLYNUCLEOTIDES ON PARTICLES Illumina, Inc. (US) 2026-05-06 EP disclosed
EP-4735624-A1 CAPTURING AND AMPLIFYING POLYNUCLEOTIDES USING PARTICLES Illumina, Inc. (US) 2026-05-06 EP disclosed
US-20040259100-A1 Methods and compositions for whole genome amplification and genotyping ILLUMINA, INC. 2004-12-23 US disclosed
US-20040259106-A1 Methods and compositions for whole genome amplification and genotyping ILLUMINA, INC. 2004-12-23 US disclosed
US-20040014096-A1 Dual-labeled nucleotides STRATAGENE 2004-01-22 US disclosed
WO-2003087302-A2 DUAL-LABELED NUCLEOTIDES STRATAGENE (US) 2003-10-23 WO disclosed
US-4086347-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIEDEMIC AGENTS, HYPOTENSIVES BOEHRINGER MANNHEIM GMBH (DT) 1978-04-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014096-A1 Dual-labeled nucleotides NT5C2, DUT, NT5E PDPK1 4196/4885GDA 116/4885CDK2 1937/4885
US-20260125412-A1 NUCLEOTIDES WITH ALPHA-IMINO PHOSPHATE GROUPS AND BRIDGING SULFURS, AND METHODS OF SYNTHESIZING AND USING THE SAME PNP, MTAP, SLC35B2 PDPK1 1004/4885GDA 796/4885CDK2 1700/4885
US-20260132223-A1 CLEAVABLE LINKERS FOR THE TETHERING OF POLYMERASES TO NUCLEOTIDES POLN, PCNA, POLB PDPK1 3823/4885GDA 621/4885CDK2 837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.