SCHEMBL5420183

SCHEMBL5420183

CN(C)c1ccc(C(=O)CCCC[O])cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.52
MAPT P10636 2/20 0.52
ALDH1A1 P00352 1/20 0.52
HSD17B3 P37058 7/20 0.47
RAB9A P51151 3/20 0.46
NPC1 O15118 2/20 0.46
HDAC3 O15379 4/20 0.46
HDAC4 P56524 4/20 0.46
HDAC1 Q13547 4/20 0.46
HDAC7 Q8WUI4 4/20 0.46
HDAC2 Q92769 4/20 0.46
HDAC10 Q969S8 4/20 0.46
HDAC11 Q96DB2 4/20 0.46
HDAC8 Q9BY41 4/20 0.46
HDAC6 Q9UBN7 4/20 0.46
HDAC9 Q9UKV0 4/20 0.46
HDAC5 Q9UQL6 4/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
LTA4H P09960 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975792 0.86 HSD17B3 (0.66) HPGDMAPTALDH1A1HSD17B3RAB9A
SCHEMBL10883603 0.84 HSD17B3 (0.67) HSD17B3HDAC3HDAC1HDAC2HDAC11
SCHEMBL14380345 0.84 HDAC3 (0.62) HPGDMAPTALDH1A1HSD17B3RAB9A
SCHEMBL8139107 0.84 HSD17B3 (0.67) HSD17B3HDAC3HDAC1HDAC2HDAC11
SCHEMBL10999955 0.84 HSD17B3 (0.67) HSD17B3HDAC3HDAC1HDAC2HDAC11
SCHEMBL6514676 0.84 HSD17B3 (0.65) HPGDMAPTALDH1A1HSD17B3HDAC3
SCHEMBL20408855 0.84 ALDH1A1 (0.53) HPGDMAPTALDH1A1HSD17B3RAB9A
SCHEMBL14380346 0.80 HDAC1 (0.70) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL11033529 0.80 HDAC1 (0.70) HDAC3HDAC4HDAC1HDAC7HDAC2
SCHEMBL10345229 0.79 HSD17B3 (0.62) HPGDMAPTALDH1A1HSD17B3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070232714-A1 Device having low outgassing photo or electron beam curable rubbery polymer material CORNING INCORPORATED 2007-10-04 US disclosed
US-7256221-B2 Low outgassing photo or electron beam curable rubbery polymer material, preparation thereof and device comprising same CORNING INCORPORATED (US) 2007-08-14 US disclosed
US-7232595-B2 Device comprising low outgassing photo or electron beam cured rubbery polymer material CORNING INCORPORATED (US) 2007-06-19 US disclosed
US-20050152595-A1 Device comprising low outgassing photo or electron beam cured rubbery polymer material CORNING INCORPORATED 2005-07-14 US disclosed
US-20040092618-A1 Low outgassing photo or electron beam curable rubbery polymer material, preparation thereof and device comprising same CORNING INCORPORATED 2004-05-13 US disclosed