⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5417453 | 0.96 | — | — | |
| SCHEMBL5427798 | 0.85 | — | — | |
| SCHEMBL5422429 | 0.83 | AGTR1 (0.48) | — | |
| SCHEMBL5426654 | 0.82 | AGTR1 (0.48) | — | |
| SCHEMBL5420492 | 0.82 | — | — | |
| SCHEMBL5417443 | 0.81 | — | — | |
| SCHEMBL5417450 | 0.79 | — | — | |
| SCHEMBL5780702 | 0.78 | AGTR1 (0.45) | — | |
| SCHEMBL5780678 | 0.76 | — | — | |
| SCHEMBL5417503 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507484-B2 | Preventive and/or therapeutic agent for neutrophilic inflammatory diseases | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-08-13 | — | — | US | disclosed |
| US-20070213361-A1 | Preventive and/or therapeutic agent for neutrophilic inflammatory diseases | KYOWA KIRIN CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1724271-A1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR NEUTROPHILIC INFLAMMATION DISEASE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-11-22 | — | — | EP | disclosed |