Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396718 | 0.90 | MAPT (0.48) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL4923913 | 0.90 | MAPT (0.59) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5402842 | 0.86 | DHODH (0.62) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5425246 | 0.83 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL5412989 | 0.82 | MAPT (0.51) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL4925177 | 0.81 | MAPT (0.58) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL4925312 | 0.79 | MAPT (0.56) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL14214419 | 0.79 | MAPT (0.55) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL4929895 | 0.78 | SCD (0.64) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL14184655 | 0.77 | MAPT (0.58) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |