Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5420599 | 0.86 | MEN1 (0.52) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4923913 | 0.85 | MAPT (0.59) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5405152 | 0.85 | MEN1 (0.48) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5364912 | 0.83 | KMT2A (0.67) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5366172 | 0.81 | PTGDR2 (0.53) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5397042 | 0.81 | KMT2A (0.58) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5409958 | 0.80 | DHODH (0.51) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4393456 | 0.80 | DHODH (0.75) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL5369173 | 0.79 | KMT2A (0.59) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4929895 | 0.79 | SCD (0.64) | DHODHMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |