SCHEMBL5420729

SCHEMBL5420729

O=C=NCCCCCC(=O)Cl

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.39
MIF P14174 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10618530 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTP53MIF
SCHEMBL11063061 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTP53MIF
SCHEMBL11062914 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTP53MIF
SCHEMBL5246659 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTP53MIF
SCHEMBL11059361 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTP53MIF
SCHEMBL11059153 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTP53MIF
SCHEMBL9714485 1.00 ALDH1A1 (0.46) ALDH1A1TSHRTP53MIF
SCHEMBL11062438 0.98 ALDH1A1 (0.43) ALDH1A1TSHRTP53
SCHEMBL9459858 0.91
SCHEMBL466441 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070219337-A1 Preparation of storage-stable, isocyanate-functional prepolymers using NCO-functional carbonyl and carbamoyl halides BAYER MATERIALSCIENCE LLC (DE) 2007-09-20 US claimed
CN-101037499-A Preparation of storage-stable isocyanate-functional prepolymers using NCO-functional carbonyl and carbamoyl halides BAYER MATERIALSCIENCE AG (DE) 2007-09-19 CN claimed
US-10870896-B2 Solid, particulate tanning agent preparations LANXESS DEUTSCHLAND GMBH (DE) 2020-12-22 US disclosed
US-9376729-B2 Compositions comprising at least one compound containing a carbamoyl sulfonate group and use of the same as tanning agents LANXESS DEUTSCHLAND GMBH (DE) 2016-06-28 US disclosed
US-20140123399-A1 SOLID, PARTICULATE TANNING AGENT PREPARATIONS LANXESS DEUTSCHLAND GMBH (DE) 2014-05-08 US disclosed
US-20130288066-A1 COMPOSITIONS COMPRISING AT LEAST ONE COMPOUND CONTAINING A CARBAMOYL SULFONATE GROUP AND USE OF THE SAME AS TANNING AGENTS LANXESS DEUTSCHLAND GMBH (DE) 2013-10-31 US disclosed
US-20070219337-A1 Preparation of storage-stable, isocyanate-functional prepolymers using NCO-functional carbonyl and carbamoyl halides BAYER MATERIALSCIENCE LLC (DE) 2007-09-20 US disclosed
CN-101037499-A Preparation of storage-stable isocyanate-functional prepolymers using NCO-functional carbonyl and carbamoyl halides BAYER MATERIALSCIENCE AG (DE) 2007-09-19 CN disclosed
CN-1782098-A Isocyanate-based tanning agents LANXESS DEUTSCHLAND GMBH (DE) 2006-06-07 CN disclosed
US-20060080784-A1 Isocyanate-based tanning agents LANXESS DEUTSCHLAND GMBH (DE) 2006-04-20 US disclosed
US-6521707-B2 (poly)ether amine ester isocyanate derivatives that can be reacted with hydroxy and amino compounds to form urethanes or ureas used in the isolation of nucleic acids BAYER AKTIENGESELLSCHAFT (DE) 2003-02-18 US disclosed
US-4886902-A HEATING POLYISOCYANATE AND AMINE WITH SILYLATED HYDROXYL GROUP; REACTING ISOCYANATE-ACID HALIDE WITH PRODUCT BAYER AKTIENGESELLSCHAFT (DE) 1989-12-12 US disclosed
US-4870198-A SILYLATED ALCOHOL OR CARBOXYL GROUPS BAYER AKTIENGESELLSCHAFT (DE) 1989-09-26 US disclosed
EP-0307756-A2 Process for the preparation of isocyanates and their use in the preparation of polyisocyanates containing ester groups, and some polyisocyanates containing these ester groups BAYER AG (DE) 1989-03-22 EP disclosed
EP-0307757-A2 Process for the production of polyurethanes with LC-properties and diisocyanates suitable for carrying out this process BAYER AG (DE) 1989-03-22 EP disclosed
EP-0302341-A2 Isocyanato-acyl urethanes, their preparation and use BAYER AG (DE) 1989-02-08 EP disclosed
US-4745212-A ESTERIFICATION OR AMIDATION OF ISOCYANATOCARBOXYL CHLORIDE BAYER AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4448816-A N-ISOCYANTOALKANOYL SUBSTITUTED CYCLIC UREAS USED IN POLYURETHANE COATINGS THE UPJOHN COMPANY (US) 1984-05-15 US disclosed
US-4188401-A Combating fungi with 1-(ω-substituted pentyl)-3-(2-cyano-acetyl)-ureas BAYER AKTIENGESELLSCHAFT (DE) 1980-02-12 US disclosed
US-4009152-A POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-02-22 US disclosed