SCHEMBL54209

SCHEMBL54209

[O]c1ccon1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082762 0.67 NPC1 (0.42)
SCHEMBL96210 0.65
SCHEMBL28836867 0.65
SCHEMBL840043 0.63
SCHEMBL115169 0.63
SCHEMBL73933 0.62
SCHEMBL73803 0.62
SCHEMBL486106 0.62
SCHEMBL19127368 0.62 ENPP2 (0.33)
SCHEMBL323163 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1068 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111801330-B Fused ring compounds having dopamine D3 receptor antagonism 盐野义制药株式会社 2024-04-05 CN claimed
CN-114763312-A Method for inducing H halogenation in C-H on benzene ring or heterocyclic ring by ultraviolet light 中国科学院大连化学物理研究所 2022-07-19 CN claimed
US-20210047315-A1 CYCLIC COMPOUND HAVING DOPAMINE D3 RECEPTOR ANTAGONISTIC EFFECT SHIONOGI & CO., LTD. (JP) 2021-02-18 US claimed
US-20210040117-A1 CONDENSED RING COMPOUNDS HAVING DOPAMINE D3 RECEPTOR ANTAGONISTIC EFFECT SHIONOGI & CO., LTD. (JP) 2021-02-11 US claimed
EP-3744721-A1 CONDENSED CYCLIC COMPOUND HAVING DOPAMINE D3 RECEPTOR ANTAGONISM Shionogi & Co., Ltd (JP) 2020-12-02 EP claimed
CN-111801330-A Fused ring compounds having dopamine D3 receptor antagonism 盐野义制药株式会社 2020-10-20 CN claimed
CN-107216242-B Method for synthesizing aromatic aldehyde, aromatic ketone and aromatic ester by oxidizing alkyl aromatic compound under catalysis of iron 南京师范大学 2020-04-03 CN claimed
US-20140243288-A1 FUSED RING-CONTAINING OXAZOLIDINONES ANTIBIOTICS Xuanzhu Pharma Co., Ltd. (CN) 2014-08-28 US claimed
EP-2762480-A1 OXAZOLIDINONE ANTIBIOTICS CONTAINING FUSED RING Xuanzhu Pharma Co., Ltd. (CN) 2014-08-06 EP claimed
EP-2704701-A1 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES Synta Pharmaceuticals Corp. (US) 2014-03-12 EP claimed
EP-0439785-B1 Substituted 2-[6-(pyrimidinyl)-indol-1-yl]-acrylic acid ester BAYER AG (DE) 1995-09-27 EP claimed
WO-1995024383-A1 OXIME DERIVATIVES AND THEIR USE AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1995-09-14 WO claimed
EP-0641768-A1 NITROXYALKYLAMIDE DERIVATIVE SANKYO COMPANY LIMITED (JP) 1995-03-08 EP claimed
US-5290668-A Photographic films with waterproof layers on supports for color photography FUJI PHOTO FILM CO., LTD. (JP) 1994-03-01 US claimed
US-5262416-A Insecticides or fungicides BAYER AKTIENGESELLSCHAFT (DE) 1993-11-16 US claimed
US-5244776-A Method of forming color images FUJI PHOTO FILM CO., LTD. (JP) 1993-09-14 US claimed
US-5212055-A Pyrazoloazole coupler, bisphenol, spirobiindane FUJI PHOTO FILM CO., LTD. (JP) 1993-05-18 US claimed
EP-0439785-A2 Substituted 2-[6-(pyrimidinyl)-indol-1-yl]-acrylic acid ester BAYER AG (DE) 1991-08-07 EP claimed
US-4051129-A REACTION OF BENZYLIDENIMINO GROUP WITH HYDRAZINE, AMIDATION SANKYO COMPANY LIMITED (JA) 1977-09-27 US claimed
US-4017488-A Process for preparing 7β-acylamino-7α-alkoxycephalosporins SANKYO COMPANY LIMITED (JA) 1977-04-12 US claimed