Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425529 | 0.96 | CHRM2 (0.39) | CHRM2GAAMAPK1SCN8AMEN1 | |
| SCHEMBL5424856 | 0.95 | CHRM2 (0.41) | CHRM2GAAMAPK1MEN1KMT2A | |
| SCHEMBL5421006 | 0.95 | CHRM2 (0.41) | CHRM2GAAMAPK1MEN1KMT2A | |
| SCHEMBL5415889 | 0.95 | CHRM2 (0.41) | CHRM2GAAMAPK1MEN1KMT2A | |
| SCHEMBL5415945 | 0.95 | CHRM2 (0.41) | CHRM2GAAMAPK1MEN1KMT2A | |
| SCHEMBL5422866 | 0.95 | CHRM2 (0.41) | CHRM2GAAMAPK1MEN1KMT2A | |
| SCHEMBL5415240 | 0.95 | CHRM2 (0.41) | CHRM2GAAMAPK1MEN1KMT2A | |
| SCHEMBL5424693 | 0.95 | CHRM2 (0.41) | CHRM2GAAMAPK1MEN1KMT2A | |
| SCHEMBL5437617 | 0.92 | GAA (0.36) | CHRM2GAAMAPK1HTR1AHTR1D | |
| SCHEMBL5434984 | 0.88 | SIGMAR1 (0.39) | CHRM2GAAHTR1AHTR1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8083965-B2 | Refrigerating machine oil | NIPPON OIL CORPORATION (JP) | 2011-12-27 | — | — | US | disclosed |
| US-20070275865-A1 | Refrigerating Machine Oil | NIPPON OIL CORPORATION (JP) | 2007-11-29 | — | — | US | disclosed |
| US-20070257229-A1 | Refrigerating Machine Oil Composition | NIPPON OIL CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |