Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343021 | 0.86 | DPP4 (0.51) | DPP4ECE1DPP8DPP7DPP9 | |
| SCHEMBL343020 | 0.86 | DPP4 (0.51) | DPP4ECE1DPP8DPP7DPP9 | |
| SCHEMBL343752 | 0.83 | ABCB1 (0.44) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL343753 | 0.83 | ABCB1 (0.44) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL344727 | 0.81 | DPP4 (0.38) | DPP4TSHRDPP8DPP7DPP9 | |
| SCHEMBL27963865 | 0.81 | DPP4 (0.38) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL28070441 | 0.81 | DPP4 (0.38) | DPP4DPP8DPP7DPP9FAP | |
| SCHEMBL27963868 | 0.78 | DPP4 (0.48) | DPP4TSHRDPP7PSEN1PSEN2 | |
| SCHEMBL368912 | 0.75 | EPHX2 (0.39) | DPP4ECE1 | |
| SCHEMBL368911 | 0.75 | EPHX2 (0.39) | DPP4ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415753-B1 | METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE | DONG A PHARM CO LTD (KR) | 2014-08-27 | — | — | EP | disclosed |
| EP-2415753-A2 | IMPROVED METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE | Dong-A Pharmaceutical Co., Ltd. (KR) | 2012-02-08 | — | — | EP | disclosed |