Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.38 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL368912 | 1.00 | EPHX2 (0.39) | EPHX2KMT2AFABP5FABP7MDM4 | |
| SCHEMBL27963868 | 0.80 | DPP4 (0.48) | DPP4 | |
| SCHEMBL542233 | 0.75 | DPP4 (0.39) | ECE1DPP4 | |
| SCHEMBL6856244 | 0.74 | KMT2A (0.41) | EPHX2KMT2AFABP5FABP7CA1 | |
| SCHEMBL6800164 | 0.74 | KMT2A (0.41) | EPHX2KMT2AFABP5FABP7CA1 | |
| SCHEMBL31524137 | 0.74 | AGTR2 (0.38) | EPHX2FABP5FABP7CHRM3 | |
| SCHEMBL13669346 | 0.73 | KMT2A (0.41) | EPHX2KMT2AFABP5FABP7CA1 | |
| SCHEMBL27415347 | 0.73 | KMT2A (0.43) | EPHX2KMT2AFABP5FABP7CA1 | |
| SCHEMBL26445925 | 0.73 | KMT2A (0.43) | EPHX2KMT2AFABP5FABP7CA1 | |
| SCHEMBL343020 | 0.73 | DPP4 (0.51) | ECE1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016125-A1 | METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE | DONG-A PHARMACEUTICAL. CO., LTD (KR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016125-A1 | METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE | DPP4, DPP3, DPP7 | EPHX2 919/4885KMT2A 3195/4885FABP5 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.