Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 2/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5423760 | 1.00 | NR1H3 (0.52) | NR1H3PLA2G4BPPARGPPARASLC2A1 | |
| SCHEMBL5423781 | 0.97 | NR1H3 (0.49) | NR1H3PLA2G4BPPARGPPARASLC2A1 | |
| SCHEMBL5423777 | 0.97 | NR1H3 (0.49) | NR1H3PLA2G4BPPARGPPARASLC2A1 | |
| SCHEMBL5422906 | 0.92 | SRD5A2 (0.50) | NR1H3PLA2G4BPPARGPPARAL3MBTL1 | |
| SCHEMBL5422910 | 0.92 | SRD5A2 (0.50) | NR1H3PLA2G4BPPARGPPARAL3MBTL1 | |
| SCHEMBL5424273 | 0.91 | HSD17B2 (0.47) | NR1H3PLA2G4BPPARGCTBP2LMNA | |
| SCHEMBL5424276 | 0.91 | HSD17B2 (0.47) | NR1H3PLA2G4BPPARGCTBP2LMNA | |
| SCHEMBL5426924 | 0.90 | PLA2G4B (0.47) | NR1H3PLA2G4BPPARGPPARAL3MBTL1 | |
| SCHEMBL5419296 | 0.90 | PLA2G4B (0.47) | NR1H3PLA2G4BPPARGL3MBTL1SMN1; SMN2 | |
| SCHEMBL5419304 | 0.90 | PLA2G4B (0.47) | NR1H3PLA2G4BPPARGL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167490-A1 | Imino ether derivative compounds and drugs containing the compounds as the active ingredient | ONO PHARMACEUTICAL CO LTD | 2007-07-19 | — | — | US | disclosed |
| EP-1602642-A1 | IMINO ETHER DERIVATIVE COMPOUNDS AND DRUGS CONTAINING THE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167490-A1 | Imino ether derivative compounds and drugs containing the compounds as the active ingredient | INSR, NR1H2, NR1H3 | NR1H3 3/4885PLA2G4B 2091/4885PPARG 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.