Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.71 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | TACR2 | P21452 | 2/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | SHBG | P04278 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.71 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.71 |
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | TST | Q16762 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685475 | 1.00 | ESR1 (0.71) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL6679954 | 1.00 | ESR1 (0.71) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL5255682 | 0.97 | ESR1 (0.67) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL6684861 | 0.95 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL1412818 | 0.95 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL23849704 | 0.95 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10571467 | 0.95 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL561020 | 0.95 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL4037557 | 0.95 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL2511615 | 0.95 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023143-A1 | INDOLE DERIVATIVES AS TESTOSTERONE-5-ALPHA-REDUCTASE INHIBITORS | PFIZER LIMITED (GB) | 1995-08-31 | — | — | WO | claimed |
| US-4695595-A | Process for the production of cellular organic silicate products | BLOUNT DAVID H | 1987-09-22 | — | — | US | claimed |
| US-4283311-A | Process for the production of broken down cellulose copolymers | BLOUNT DAVID H | 1981-08-11 | — | — | US | claimed |
| EP-0025051-A1 | PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER | BLOUNT, David H. (US) | 1981-03-18 | — | — | EP | claimed |
| WO-1980001919-A1 | PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER | BLOUNT D (US) | 1980-09-18 | — | — | WO | claimed |
| US-4197229-A | USED AS COATINGS, MOLDING MATERIALS, CAULKING COMPOUNDS | BLOUNT DAVID H | 1980-04-08 | — | — | US | claimed |
| US-7268267-B2 | Alkylation process using UZM-8 zeolite | UOP LLC (US) | 2007-09-11 | — | — | US | disclosed |
| US-20060224031-A1 | Alkylation process using UZM-8 zeolite | UOP LLC | 2006-10-05 | — | — | US | disclosed |
| EP-0985649-B1 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-6462248-B1 | THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS | TORAY INDUSTRIES, INC. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-0985649-A2 | Method for producing an aromatic compound having an alkyl group with at least three carbon atoms | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-4769396-A | Process for the production of cellular organic silicate products | BLOUNT DAVID H (US) | 1988-09-06 | — | — | US | disclosed |
| US-4695595-A | Process for the production of cellular organic silicate products | BLOUNT DAVID H | 1987-09-22 | — | — | US | disclosed |
| US-4321184-A | FROM OXIDATED SILICON COMPOUNDS AND SUBSTITUTED ORGANIC COMPOUND IN PORESENCE OF AN ALKALI COMPOUND | BLOUNT DAVID H | 1982-03-23 | — | — | US | disclosed |
| US-4314916-A | Process for the production of broken down lignin-cellulose silicate copolymers | BLOUNT DAVID H | 1982-02-09 | — | — | US | disclosed |
| US-4283311-A | Process for the production of broken down cellulose copolymers | BLOUNT DAVID H | 1981-08-11 | — | — | US | disclosed |
| US-4281110-A | Process for the production of broken down lignin-cellulose silicate copolymers | BLOUNT DAVID H | 1981-07-28 | — | — | US | disclosed |
| EP-0025051-A1 | PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER | BLOUNT, David H. (US) | 1981-03-18 | — | — | EP | disclosed |
| WO-1980001919-A1 | PROCESS FOR THE PRODUCTION OF AN AQUEOUS DISPERSION OF POLY(ORGANIC-POLYSULFIDE-SILICATE)COPOLYMER | BLOUNT D (US) | 1980-09-18 | — | — | WO | disclosed |
| US-4197229-A | USED AS COATINGS, MOLDING MATERIALS, CAULKING COMPOUNDS | BLOUNT DAVID H | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060224031-A1 | Alkylation process using UZM-8 zeolite | UFM1, USP8, ADRM1 | ESR1 2195/4885ADRA2A 665/4885ADORA3 3393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.