Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL8076405 | 1.00 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL10400155 | 0.95 | SLC34A1 (0.54) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL14780298 | 0.95 | SLC34A1 (0.54) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL7918052 | 0.91 | SLC34A1 (0.61) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL11508273 | 0.91 | SLC34A1 (0.61) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL17937932 | 0.90 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL2822272 | 0.90 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL515729 | 0.90 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL11072030 | 0.90 | SLC34A1 (0.58) | SLC34A1LMNAKDM4ECYP2C19KMT2A | |
| Phosphoric Acid SCHEMBL8670758 | 0.90 | SLC34A1 (0.73) | SLC34A1LMNAKDM4ECYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253303-A | Method for directly separating impurities from solid lithium phosphate | 佛山市德方纳米科技有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-115990288-A | Fish scale-based bioactive patch and preparation method and application thereof | 中国科学院上海硅酸盐研究所 | 2023-04-21 | — | — | CN | disclosed |
| US-11377706-B2 | Device to improve iron loss properties of grain-oriented electrical steel sheet | JFE STEEL CORPORATION (JP) | 2022-07-05 | — | — | US | disclosed |
| CN-112891622-A | Porous calcium-magnesium dual-phase ceramic microsphere and preparation method thereof | 武汉理工大学 | 2021-06-04 | — | — | CN | disclosed |
| CN-112245656-A | Preparation method of calcium phosphate magnesium bone cement composite scaffold | 武汉理工大学 | 2021-01-22 | — | — | CN | disclosed |
| US-20200332380-A1 | DEVICE TO IMPROVE IRON LOSS PROPERTIES OF GRAIN-ORIENTED ELECTRICAL STEEL SHEET | JFE STEEL CORPORATION (JP) | 2020-10-22 | — | — | US | disclosed |
| US-10745773-B2 | Device to improve iron loss properties of grain-oriented electrical steel sheet | JFE STEEL CORPORATION (JP) | 2020-08-18 | — | — | US | disclosed |
| CN-106359603-A | Method for producing diary product with determined lactose amount | DMK德意志牛奶股份有限公司 | 2017-02-01 | — | — | CN | disclosed |
| US-9346123-B2 | Device to improve iron loss properties of grain oriented electrical steel sheet and method for improving iron loss properties of grain oriented electrical steel sheet | JFE STEEL CORPORATION (JP) | 2016-05-24 | — | — | US | disclosed |
| EP-2799561-A1 | DEVICE TO IMPROVE IRON LOSS PROPERTIES OF GRAIN-ORIENTED ELECTRICAL STEEL SHEET | JFE Steel Corporation (JP) | 2014-11-05 | — | — | EP | disclosed |
| US-20140312009-A1 | DEVICE TO IMPROVE IRON LOSS PROPERTIES OF GRAIN-ORIENTED ELECTRICAL STEEL SHEET | JFE STEEL CORPORATION (JP) | 2014-10-23 | — | — | US | disclosed |
| US-20130161301-A1 | DEVICE TO IMPROVE IRON LOSS PROPERTIES OF GRAIN ORIENTED ELECTRICAL STEEL SHEET AND METHOD FOR IMPROVING IRON LOSS PROPERTIES OF GRAIN ORIENTED ELECTRICAL STEEL SHEET | JFE STEEL CORPORATION (JP) | 2013-06-27 | — | — | US | disclosed |
| US-20070166466-A1 | Water-based heat-resistant coating composition and process for applicant thereof | KANSAI PAINT CO., LTD. (JP) | 2007-07-19 | — | — | US | disclosed |