Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | HTR6 | P50406 | 4/20 | 0.74 |
| ▸ | RECQL | P46063 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | DRD2 | P14416 | 3/20 | 0.74 |
| ▸ | HTR2A | P28223 | 3/20 | 0.74 |
| ▸ | HTR2C | P28335 | 3/20 | 0.74 |
| ▸ | DRD3 | P35462 | 3/20 | 0.74 |
| ▸ | HTR2B | P41595 | 3/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.74 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.74 |
| ▸ | DRD1 | P21728 | 2/20 | 0.74 |
| ▸ | CASP1 | P29466 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26265120 | 1.00 | HSD17B10 (0.74) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL11208707 | 0.94 | HSD17B10 (0.72) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL11209308 | 0.94 | HSD17B10 (0.71) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL26265117 | 0.92 | MEN1 (0.71) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL670696 | 0.90 | HTR6 (0.76) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL13475442 | 0.90 | HTR6 (0.76) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL31079449 | 0.90 | HTR6 (0.76) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL30417228 | 0.89 | HTR6 (0.70) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL26265139 | 0.88 | HTR6 (0.81) | HSD17B10MEN1KMT2ACYP2D6KDM4E | |
| SCHEMBL25545437 | 0.87 | MEN1 (0.79) | HSD17B10MEN1KMT2ACYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014186623-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF A CHAGAS DISEASE | BIOMED VALLEY DISCOVERIES (US) | 2014-11-20 | — | — | WO | claimed |
| CN-106565702-A | Method for preparing lysergic acid through hydrolysis | 重庆乾泰生物医药有限公司 | 2017-04-19 | — | — | CN | disclosed |
| WO-2014186623-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF A CHAGAS DISEASE | BIOMED VALLEY DISCOVERIES (US) | 2014-11-20 | — | — | WO | disclosed |
| US-20070135638-A1 | Process for the manufacture of lysergic acid | IVAX PHARMACEUTICALS S.R.O. (CZ) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135638-A1 | Process for the manufacture of lysergic acid | LPAR5, LPAR2, LPAR1 | HSD17B10 3037/4885MEN1 1860/4885KMT2A 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.