Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.77 |
| ▸ | MEN1 | O00255 | 7/20 | 0.77 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 6/20 | 0.73 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | PLG | P00747 | 3/20 | 0.68 |
| ▸ | KLK1 | P06870 | 2/20 | 0.68 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.64 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.64 |
| ▸ | PLAU | P00749 | 2/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.63 |
| ▸ | F10 | P00742 | 1/20 | 0.63 |
| ▸ | PLAT | P00750 | 1/20 | 0.63 |
| ▸ | ALPL | P05186 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5426499 | 0.92 | KMT2A (0.84) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL15478030 | 0.87 | KMT2A (0.77) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL57970 | 0.87 | MEN1 (0.77) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL29890853 | 0.87 | MEN1 (0.77) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL30084384 | 0.87 | MEN1 (0.77) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL10967705 | 0.87 | MEN1 (0.64) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL2129288 | 0.85 | P2RX1 (0.71) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL10597427 | 0.84 | KMT2A (0.73) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL10865627 | 0.84 | NPC1 (0.73) | KMT2AMEN1RAB9ANPC1POLB | |
| SCHEMBL2743095 | 0.84 | NPC1 (0.73) | KMT2AMEN1RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8653086-B2 | Naphthamides as anticancer agents | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-8653086-B2 | Naphthamides as anticancer agents | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2014-02-18 | — | — | US | disclosed |
| US-7989498-B2 | Immunosuppressants; autoimmune disease; organs transplantation; antiinflammatory agents; viricides; antiproliferative agents; antitumor, anticancer agents | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-02 | — | — | US | disclosed |
| US-7989498-B2 | Immunosuppressants; autoimmune disease; organs transplantation; antiinflammatory agents; viricides; antiproliferative agents; antitumor, anticancer agents | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-08-02 | — | — | US | disclosed |
| US-7915255-B2 | Metabolism-modulating agents and uses therefor | VERVA PHARMACEUTICALS PTY LTD (AU) | 2011-03-29 | — | — | US | disclosed |
| US-7915255-B2 | Metabolism-modulating agents and uses therefor | VERVA PHARMACEUTICALS PTY LTD (AU) | 2011-03-29 | — | — | US | disclosed |
| EP-0190947-B1 | PROCESS FOR PRODUCING AZO PIGMENTS | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1990-01-31 | — | — | EP | disclosed |
| US-4655844-A | COUPLING AROMATIC DIAZONIUM COMPOUND WITH 3-HYDROXY-2-NAPHTHOIC ACID AND A BIS-NAPHTHYLAMETHANE | KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) | 1987-04-07 | — | — | US | disclosed |
| EP-0190947-A2 | Process for producing azo pigments | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1986-08-13 | — | — | EP | disclosed |